Osaka [Japan], February 20 (ANI): Researchers have found that dipeptides containing 2-oxo-imidazole (2-oxo-IDPs) have extraordinarily important antioxidant exercise. Also, they developed a way to particularly and sensitively detect very minute concentrations of 2-oxo-IDPs and found for the primary time that a number of types of 2-oxo-IDPs are contained in meat, together with beef, pork, and hen.
Imidazole dipeptides (IDPs), that are considerable in meat and fish, are substances produced within the our bodies of varied animals, together with people, and have been reported to be efficient in relieving fatigue and stopping dementia. However, the physiological mechanism by which IDPs exhibit these actions had not been decided beforehand.
A analysis staff, led by Professor Hideshi Ihara from the Osaka Metropolitan University Graduate School of Science, was the primary to find 2-oxo-imidazole-containing dipeptides (2-oxo-IDPs) — which have yet another oxygen atom than regular IDPs — and located that they’re the commonest number of IDPs derivatives within the physique. The researchers additionally discovered that they’ve remarkably excessive antioxidant exercise.
In their examine, the researchers established a way for selective and extremely delicate detection of 5 varieties of 2-oxo-IDPs utilizing mass spectrometry, which allows quantitative detection of hint 2-oxo-IDPs in residing organisms. Using this technique, they revealed for the primary time that beef, pork, hen, and different meats include antioxidants, not solely IDPs however a wide range of completely different 2-oxo-IDPs. Their findings have been revealed in Antioxidants.
“We hope that this research method, which enables advanced analysis of 2-oxo-IDPs, will be applied not only to basic biology but also to medicine, agriculture, and pharmacy, where it will help improve peoples’ health and prevent diseases,” mentioned Professor Ihara. (ANI)